Olerup SSP

Olerup SSP produces products for PCR-based tissue typing of HLA. The products are used to match patients and donors in hematopoietic stem cell (blod stem cells or bone marrow transplantation) and organ transplantation

Olerup SSP was founded in 1992 by transplantation physician and associate professor Olle Olerup, who at the time was working at Huddinge Hospital in Stockholm. Over the years he has built up a company that is well-positioned in international markets, has a well known brand and strong proprietary expertise in HLA typing.

OLERUP SSPs HLA-typining kits

Olerup SSP’s HLA typing kits have been CE marked as an IVD (In Vitro Diagnostic Medical Device) for many years, certification that is required for sales in Europe. In 2009, the products received FDA 510 (k) registration, clearing them for sales in the U.S. Clearance was also granted by Health Canada in 2009 allowing sales of the products in Canada.

Olerup SSP provides a test system for the typing of HLA alleles using the PCR (Polymerase Chain Reaction)-SSP (Single Specific Primer) method. The SSP typing method uses the PCR as a system to amplify DNA sequences with the help of specific primers that bind only to a complementary DNA sequence. In contrast, non-complementary primers do not bind to the DNA and no amplification takes place. Detection of an amplified DNA is done using gel electrophoresis.

PCR-SSP works for all HLA loci, providing fast, accurate results with a high level of resolution

Olerup SSP currently offers around 115-120 different typing kits, covering the approximately 6,000 different HLA alleles that have been identified to date. Approximately five new HLA alleles are identified per day. It takes one to a few months to update all the kits for the new alleles.

Olerup SSP offers both products for high-resolution and low resolution HLA typing with very low frequency of false positive and false negative reactions.

Distribution and Sales

Distribution and sales through Olerup GmbH and Olerup Inc.